Feb 1, 2024 · For oral dosage form (extended-release capsules): Adults, teenagers, and children 12 years of age and older weighing more than 45 kilograms (kg)—At first, 300 to 400 milligrams (mg) as a single dose, usually in the morning, or divided and given two times per day
014 mg/kg) is more effective and less toxic than intravenous theophylline
Oral Liquid: Adults Without Risk Factors for Impaired Clearance: Initial dose: 300 mg per day given as evenly divided doses every 6 to 8 hours After 3 days, if starting dose was tolerated: 400 mg per day given as evenly divided doses every 6 to 8 hours After 3 more days, if tolerated: 600 mg per day given as
For children: 5 to 15 mcg/mL For adults: 10 to 20 mcg/mL Toxic serum concentration: greater than 20 mcg/mL
USES: Theophylline is used to treat lung diseases such as asthma and COPD (bronchitis, emphysema)
The serum concentration of Theophylline can be increased when it is combined with Sulfamethoxazole
Theophylline is a long-acting bronchodilator
Theophylline (Oral Route) It is very important that your doctor check the progress of you or your child at regular visits, especially for the first few weeks after you
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As theophylline monohydrate modified-release tab: ≥6 years Usual maintenance dose: 9 mg/kg bid
If administering aminophylline, increase dose by 25% (aminophylline is approximately 79-86% theophylline) For oral loading, use immediate-release theophylline or aminophylline; Side effects of theophylline at peak serum concentration less than 20 mcg/mL include: Central nervous system excitement, headache, insomnia, irritability Theophylline is used together with other medicines to treat the symptoms of asthma, bronchitis, emphysema, and other lung diseases
Theophylline belongs to a group of medicines known as bronchodilators
In a 14 week continuous breeding study, theophylline, administered to mating pairs of B6C3F 1 mice at oral doses of 120, 270 and 500 mg/kg (approximately 1
Other dosage forms: Some side effects of theophylline may occur that usually do not need medical attention
It is given by mouth in the form of a tablet or liquid, or in hospital as an injection
0- 3
0 times the human dose on a mg/m 2 basis) impaired fertility, as evidenced by decreases in the number of live pups per litter, decreases in the mean number of litters per fertile pair Drug Levels
8 = 672mg of oral theophylline daily; 672mg ÷ 2 = 336mg oral theophylline to give twice a day; A suitable regimen for this individual could be 300mg oral theophylline in the morning and 400mg
Theophylline extended-release tablets in Japan