Therapy with venlafaxine should be administered cautiously in patients with impaired renal and/or hepatic function
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For oral dosage forms (extended-release capsules, extended-release tablets): For depression: Adults—At first, 75 milligrams (mg) per day, taken as one dose in the morning or evening
It comes in two forms: immediate-release (treats depression) and extended-release (treats Renal Impairment Oral
Approximately 87% of a venlafaxine dose is recovered in the Effexor is an antidepressant that may cause a discontinuation syndrome if abruptly stopped after long-term administration
If you cannot swallow the capsule whole, the capsule may be opened and the contents
yellow eyes or skin
Adults with renal impairment (GFR: 10 to 70 mL/minute): Venlafaxine: Clearance is decreased by ~24%; ODV: Clearance unchanged versus normal subjects In patients with Child-Pugh class A and Child-Pugh class B hepatic impairment, venlafaxine oral bioavailability was increased 2- to 3-fold
In a recently updated Cochrane review on the use of antidepressants in the physically ill, Rayner et al
Venlafaxine is an antidepressant drug in a class called serotonin-norepinephrine reuptake inhibitors (SNRIs)
It's not common, but some people (less than 1 in 100) may have serious side effects when taking venlafaxine
In dialysis patients, venlafaxine elimination half-life was prolonged by about
See full prescribing information for Renal impairment: reduce the total daily dose by 25% to 50% in patients with renal impairment
You will usually take slow release tablets or capsules once a day