Unblinded adaptive randomised control trial; Following written consent from the patient
A Trial of Tandem Autologous Stem Cell Transplants +/- Post • Segment B - 2nct Autologous Transplant and Dexamethasone/ Thalidomide Maintenance Therapy
Steroids had been proposed as well, but a well designed, randomized study was needed to demonstrate their efficacy in Covid-19
Multiple treatment options have been approved/authorized since the results of the RECOVERY trial were published
The RECOVERY trial is a well-designed study with over 6000 patients recruited across 170 NHS trusts for the dexamethasone arm of the trial
Since then it has identified four life-saving treatments for COVID-19, and shown that several other commonly used treatments were not effective
This is a massive 176-center, randomized, open-label, pragmatic trial comparing several treatments to usual care for patients hospitalized with COVID-19
On the second anniversary of its official launch
0 1 Intervention Dexamethasone 6mg (equivalent to prednisolone 38 mg) once daily for 10 days or until The trial intervention (dexamethasone) is stopped on the day of hospital discharge, or at Day 10 whichever is sooner
3 Mortality at 28 days was lower among the patients who received dexamethasone than among those
Within hours, the result was breaking news across the world and hospitals were adopting the drug into the
Statement from the RECOVERY trial chief investigators, 5 March 2021
The enrollment of patients in the hydroxychloroquine group was closed on June 5, 2020, after an interim analysis determined that there was a lack of efficacy