5 to 5 mg IV bolus over 2 minutes, up to 3 doses: 5 minutes: Tarssanen L
When switching a patient from tablets to liquid, the same total daily dose may be used but divided in smaller, more frequent, doses (8)
25 mg/kg over 2 min
Due to post-dosing Na + retention, IV loop-diuretic agents should usually be given at least twice daily
Decrease in-hospital dose by 50% if sinus <50 bpm; d/c if sinus <40 bpm or symptoms
Some facilities also include cardiac and neurologic medications in their programs Inclusion Criteria for IV to PO Conversion: Infections that Require IV Antibiotics Must satisfy below criteria: • Tolerate oral diet or enteral nutrition Levothyroxine† Dose varies Daily Double IV dose Daily Fluconazole 100 - 400 mg Q24h Same dose Same frequency Methocarbamol‡ 1000 mg Q8h 750 mg Q8h Levofloxacin 250 - 750 mg Q24h Same The digoxin concentration is likely to be 10-25% lower when sampled right before the next dose (24 hours after dosing) compared to sampling 8 hours after dosing (using once-daily dosing)
The digoxin in capsules tended to be better absorbed than the reference tablets
Reduced nursing preparation and administration time
Canadian Brand Name
Use suppositories if no enteral tube (licensed for up to 7 days) Lacosamide Tablets Syrup 10mg/ml Injection (IV) Equivalent dose4 (all formulations) Syrup can be administered via enteral tube