Chloroquine resistance 2017

Emergence of chloroquine (CQ) resistance among different strains of Plasmodium falciparum is the worst catastrophe that has ever perplexed the dedicated efforts to eradicate malaria. and 2017, Guyana reported a validated molecular marker (C580Y) associated with partial artemisinin resistance

2024-03-28
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  1. Chloroquine is the first-line treatment for uncomplicated P
  2. 76; IC 95%: 0
  3. 22%) were found to be resistant to chloroquine
  4. The sequencing success rate for pfmdr1 amplicons ranged from 81 to 95%
  5. falciparum resistance to chloroquine is almost established [11, 12]
  6. Of the four human malaria parasite species, only P
  7. vivax chloroquine-resistance transporter), pvdhps (P
  8. 1073/pnas
  9. 14127
  10. falciparum chloroquine resistance transporter (Pfcrt), P