Propranolol and reduction of metastasis

However, there is May 26, 2020 · Besides regulating processes such as blood pressure, heart rate, and airway strength or reactivity, beta-blockers block mechanisms that trigger tumorigenesis, angiogenesis, and tumor metastasis. Jun 13, 2020 · Indeed, preclinical in vitro and in vivo studies have shown that inhibition of β-adrenergic signaling and/or prostaglandin synthesis can reduce the immunosuppressive and prometastatic effects of stress and surgery in several tumor lines and models, 4, 5 including liver metastases of colon cancer

2024-03-29
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  2. The reduction in metastatic spread was especially notable (OR, 0
  3. 05) in migration
  4. Article