It is used for the treatment of a wide range of infections including urinary tract infections caused by
Gram-negative bacillary sepsis with shock has a mortality rate of 12 to 38 percent; mortality varies
Gram-positives: Ciprofloxacin and levofloxacin are excreted in the kidney (with good efficacy against urinary tract infection)
gonorrhoeae that are susceptible Ciprofloxacin is used to treat or prevent certain infections caused by bacteria such as pneumonia; gonorrhea (a sexually transmitted disease); typhoid fever (a serious infection that is common in developing countries); infectious diarrhea (infections that cause severe diarrhea); and infections of the skin, bone, joint, abdomen (stomach area), and prostate
Weight at least 38 kg: 500 to 750 mg orally every 8 to 12 hours
Microbiology: Ciprofloxacin has in vitro activity against a wide
This would suggest that by adding ciprofloxacin to piperacillin-tazobactam, the likelihood of covering a gram-negative rod increases from 88% to 98%
and Listeria spp
and Pseudomonas aeruginosa after an increase in minimal inhibitory concentrations (MICs) to FQ among Gram-negative bacteria (GNB), application of
The dose of ciprofloxacin was 200 mg by intravenous infusion, over 30 minutes, every 12 hours for 10 days
The primary mechanism of action of ciprofloxacin is inhibition of bacterial DNA gyrase
FDA safety warning regarding fluoroquinolone use
Since its introduction in the 1980s, most Gram-negative bacteria have remained highly susceptible to this agent in vitro; Gram-positive bacteria are generally susceptible or moderately susceptible
33 mg equivalent to 3 mg base