According to some estimates, NSAIDs can successfully treat this defect in about 67% of infants
Indomethacin has a protective effect on the incidence of intraventricular hemorrhage (IVH) but reduces the blood flow to the Non-selective COX-inhibitors such as flurbiprofen, indomethacin and ibuprofen may be used
tb111959
200mg bid
Side effects such as stomach upset, nausea, or ulcers may be more likely to occur
Combining these medications may increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation
Effect of ibuprofen and indomethacin on bone metabolism reflected in bone strength
NSAIDs available only by prescription are celecoxib, diclofenac, indomethacin, and sulindac (see Table 1 for a longer list and brand names)
For mild to moderate acute pain: Adults—20 milligrams (mg) three times a day, or 40 mg two or three times a day
Head-to-head comparisons of medication uses, side effects, warnings, and more
Dosage Guidelines & Tips Blood level of ibuprofen increase 1 to 2 h after ingestion and its absorption occurs immediately after oral administration
In case of allergy or intolerance to
Indomethacin is associated with more side effects, and it is usually considered for recurrences
Indomethacin
We compared the distribution of predictor variables and the outcomes of interest between infants exposed to indomethacin versus ibuprofen using Wilcoxon rank sum and chi-square tests of association