5 mg of fosphenytoin sodium is equivalent to 1 mg phenytoin sodium, and is referred to as 1 mg phenytoin sodium equivalents (PE)
Phenytoin Sodium Equivalents (PE) The dose, concentration, and infusion rate of CEREBYX should always be expressed as phenytoin sodium equivalents (PE)
Cerebyx (fosphenytoin sodium) Injection is an anti-epileptic drug, also called an anticonvulsant, used to prevent or control seizures
5 mg of fosphenytoin sodium is equivalent to 1 mg phenytoin sodium, and
Phenytoin is a hydantoin derivative, a first-generation anti-convulsant drug that is effective in the treatment of generalized tonic-clonic seizures, complex partial seizures, and status epilepticus without
Fosphenytoin (Cerebyx) Fosphenytoin is a phosphate ester prodrug of phenytoin developed as a replacement for standard injectable sodium phenytoin
Monitor: phenytoin level 2 hr after IV, 4 hr after IM
CEREBYX ® (fosphenytoin sodium injection) is a prodrug intended for parenteral administration; its active metabolite is phenytoin
5 mg of fosphenytoin sodium is equivalent to 1 mg phenytoin sodium, and is referred to as 1 mg phenytoin sodium equivalents (PE)
2 Lactation 8
Measurement of plasma phenytoin levels is recommended only after the complete conversion of the drug due to the cross-reactivity of fosphenytoin in the immunoassay
1
The amount and concentration of fosphenytoin is always expressed in terms of mg of
N/A LCM or FOS VPA LCM or FOS N/A N/A N/A Fosphenytoin None - see
Objective: We aim to compare the intravenous and intramuscular bioavailability and safety between CE-fosphenytoin sodium, fosphenytoin sodium (Cerebyx®), and phenytoin sodium
CEREBYX® (fosphenytoin sodium injection) is a prodrug intended for parenteral administration; its active metabolite is phenytoin
Objective: We aim to compare the intravenous and intramuscular bioavailability and safety between CE-fosphenytoin sodium, fosphenytoin sodium (Cerebyx ®), and phenytoin sodium
Thus, 100 mg PE of fosphenytoin and 100 mg of phenytoin yield the same molar amounts of phenytoin sodium
The “Sheiner-Tozer Equation” is the official name of this correction
Fosphenytoin is metabolized to phenytoin, phosphate and formate
The mechanism of fosphenytoin conversion has not been determined, but phosphatases probably play a
Fosphenytoin was