An increasing amount of evidence has suggested that low-dose theophylline has anti-inflammatory and immunomodulatory effects in asthma and COPD 2, 3, and
Introduction Theophylline remains one of the most widely prescribed drugs for the treatment of asthma and COPD world-wide, since it is inexpensive and
theophylline are rapid and complete, with peak levels achieved at 2 h after administration
They provide immediate relief for acute
Theophylline is a bronchodilator that is used to treat symptoms of asthma, bronchitis, emphysema, and other breathing problems
Theophylline, a drug that has been used for several decades, has several different actions at a cellular level, including inhibition of phosphodiesterase isoenzymes, antagonism of adenosine, enhancement of catecholamine secretion, and modulation of calcium fluxes
0–102
15% max residue on ignition; and melting-point, 270–274°C ( US Doxofylline
Introduction
A study in which theophylline (anhydrous) extended-release 400 mg tablets were administered to 17 fed adult asthmatics produced similar theophylline level-time curves when administered in the morning or evening
Oral theophylline was commonly used in treatment of acute attacks of asthma and in chronic management of bronchospasm in patients with asthma and chronic obstructive pulmonary disease, but
0 times the human dose on a mg/m 2 basis) impaired fertility, Theophylline is a relatively weak bronchodilator, is less effective than an inhaled beta-2 selective agonist
The remaining unbound theophylline distributes freely throughout the body except for body fat
In a 14 week continuous breeding study, theophylline, administered to mating pairs of B6C3F 1 mice at oral doses of 120 mg/kg, 270 mg/kg and 500 mg/kg (approximately 1
Side Effects
In a 14 week continuous breeding study, theophylline, administered to mating pairs of B6C3F 1 mice at oral doses of 120, 270 and 500 mg/kg (approximately 1
Blinding of some kind took place in 37 study arms, with blinding being unclear in Subjects enrolled in the longitudinal study will complete surveys and the objective smell test UPSIT every month until a subject’s UPSIT test is in the normal smell range or for a total of five months
Aminophylline is a bronchodilator consisting of theophylline that is used for the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis
Such preparations, often with a mild sedative added, dominated the
Theophylline (Oral Route) Theophylline is used together with other medicines to treat the symptoms of asthma, bronchitis, emphysema, and other lung diseases
More serious effects are haematemesis, convulsions, and supraventricular and ventricular arrhythmias
After removal of duplicates, 841 studies were screened and 55 studies were included