Symptoms of this reaction include copious nausea and vomiting, severe headaches, flushing, dizziness, sweating, and chest pain
S
Throbbing headache
Disulfiram is a thiuram derivative which blocks the oxidation of alcohol at the acetaldehyde stage
Today, Antabuse is typically replaced or used with newer drugs like Revia, Vivitrol (naltrexone), and Campral (acamprosate)
Within minutes after alcohol is consumed, a combination of the following symptoms can occur: Usual Adult Dose for Alcohol Dependence
Other side effects not listed may also occur in some patients
While taking this medication, avoid alcohol in all forms including Disulfiram In Treating Alcoholism
Along with its needed effects, disulfiram may cause some unwanted effects
Because of risk of accidental disulfiram-alcohol reaction, use with extreme caution in patients with
It is suggested that every patient under treatment carry an Identification Card stating that he is receiving disulfiram and describing the symptoms
Disulfiram-induced psychosis may be more common at doses of 500 mg/day than at lower doses
(Cards may be obtained from Disulfiram blocks the oxidation of alcohol at the acetaldehyde stage during alcohol metabolism following disulfiram intake causing an accumulation of acetaldehyde in the blood producing highly unpleasant symptoms
5%) developed psychotic symptoms; these symptoms remitted after disulfiram discontinuation
inhibited) isoflurane
A disulfiram-like drug is a drug that causes an adverse reaction to alcohol leading to nausea, vomiting, flushing, dizziness, throbbing headache, chest and abdominal discomfort, and general hangover -like symptoms among others
In adults, clinical manifestations after acute overdose are rare with doses less than 3 g
Disulfiram (tetraethylthiuram disulfide [TETD]) has been used for more than 50 years as a deterrent to ethanol abuse in the management of alcoholism