The frequency and severity of side effects in paroxetine patients declined markedly from short-term to long-term treatment, whereas changes in imipramine
OBJECTIVE: This is an analysis of the unpublished continuation phase of Study 329, the primary objective of which was to compare the efficacy and
In adolescents with major depression, paroxetine was more effective than placebo for improving depression related outcomes on the 17 item Hamilton Rating Scale
The Potency theory says paroxetine and
It is used in the treatment of hot flashes
5 mg) were significantly more effective than placebo; they were comparably effective at weeks 6, 8, and 12 according to the intent-to-treat analysis and at week 8 according to the analysis for the subjects who completed the trial (for them, only imipramine was superior to The economic impact of paroxetine and imipramine treatment of depressed outpatients from a university teaching hospital and a community mental health center was compared and no significant difference was revealed in the total cost between the two groups
These medicines are thought to work by increasing the activity of a chemical called serotonin in the brain
Results The efficacy of paroxetine and imipramine was not statistically or clinically significantly different from placebo for any prespecified primary or secondary efficacy outcome
0 (7
7) points, respectively, for the information on the safety profile of paroxetine and imip - ramine when these drugs were given for “an extended period of time ”; and to estimate the rate of relapse among patients who responded to imipramine, paroxetine, and placebo and were maintained on treatment
The main goal of the present study was to evaluate the influence of caffeine on animals’ behavior in forced swim test (FST) as well as the effect of caffeine (5 mg/kg) on the activity of six typical antidepressants, such as imipramine (15 mg/kg), desipramine (10 mg/kg), fluoxetine (5 mg/kg), paroxetine (0
However, paroxetine appeared to have a possibly greater and earlier beneficial effect on anxiety symptoms associated with depression, when compared with imipramine
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Paroxetine is a selective serotonin uptake inhibitor, which is being investigated as an antidepressant
Paroxetine is a novel antidepressant that selectively inhibits neuronal reuptake of serotonin
In contrast to controls, on the day after the acute injection, both imipramine- and paroxetine-treated rats were unable to discriminate the old from the recent objects
A relapse prevention study of 325 patients conducted with escitalopram and paroxetine included 8 weeks of initial treatment, followed by a 19-week maintenance treatment period and finally a 1–2 week tapered discontinuation period (Baldwin et al
Cohn and Louis F