See more Some statins
Takeaway Eating grapefruit may negatively interact with certain statin drugs, such as atorvastatin, lovastatin, and simvastatin
The U
Grapefruit and grapefruit juice may interact with simvastatin and lead to unwanted side effects
Major Food Interaction
Zocor (simvastatin) is a brand-name oral tablet prescribed to lower cholesterol and triglyceride levels and reduce certain heart-related risks
2 litres daily), but an occasional glass is thought to be safe
When ZETIA is used in combination with a statin, fenofibrate, or other HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information
Grapefruit products are known to interact with several medications, and one of which is simvastatin
Zocor has interactions with some other drugs and There was a marked interindividual variability in the grapefruit juice–simvastatin interaction, e
As shown in Figure 2, 62% of statin users never heard about the statin–grapefruit interaction
Zocor will not be as effective in lowering your cholesterol if you do not follow a cholesterol-lowering diet plan
And be sure to keep an updated medication list so they can screen for any possible interactions
That’s because grapefruit affects an enzyme that normally breaks statins down
This can increase the risk of side effects such as liver damage and a rare but serious condition called rhabdomyolysis that involves the breakdown of skeletal muscle tissue
What Medications Interact with Grapefruit Juice? Keep in mind that the extent of the interaction varies by person, medicine, and the amount of grapefruit juice you drink
It has a big impact on atorvastatin (Lipitor), lovastatin (Mevacor) and simvastatin (Zocor), but little or no effect on fluvastatin (Lescol), pitavastatin (Livalo), pravastatin (Pravachol) and rosuvastatin (Crestor)
If you’re taking a statin, you may need to avoid grapefruit and grapefruit juice — but it depends on what kind of statin you’re taking
After you take a dose of Lipitor, your body Grapefruit interactions: One of the more well-known food-drug interactions involves grapefruit and grapefruit juice and certain cholesterol-lowering statin medications — namely, atorvastatin Interactions
This enzyme system in the liver is well known for its involvement with drug-drug interactions
Bergamottin (BG) and naringenin (NRG) could therefore be applied as markers in food-drug interaction studies in order to adjust posology and the dose of simvastatin
Atorvastatin is the generic name for a widely prescribed statin medication, originally prescribed under the brand name Lipitor