A new model aqueous solution of indomethacin was developed on the basis of Pluronic F68 (15%) and F127 (10%)
A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders Purpose: The objective of the present study was to formulate indomethacin (IN)-loaded solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) and to investigate their potential use in topical ocular delivery
An attempt has been made to formulate indomethacin ophthalmic inserts using hydroxy propyl methyl cellulose, methyl cellulose and gelatin as polymers by solvent casting method with aim of Indomethacin ophthalmic suspension: Indom® and Indocollirio® Indomethacin, one of the most commonly used non-steroidal anti-inflammatory drug (NSAIDs), is employed for maintaining mydriasis during cataract surgery and reduction of discomfort after refractive surgery or in allergic conjunctivitis
Both groups received t
5% indomethacin solid nanoparticles (high content type), and found that three energy-dependent endocytosis pathways (CavME, CME and MP) are related to the transcorneal penetration of indomethacin nanoparticles; in particular, the CavME pathway is strongly
Indomethacin concentrations in the rabbit aqueous humor after topical administration of the suspensions
Chitosan/sulfobutylether-β-cyclodextrin based nanoparticles coated with thiolated hyaluronic acid for indomethacin ophthalmic delivery
Publication types Ophthalmic Solutions Postoperative Care Preoperative Care We previously developed ophthalmic formulations containing tranilast nanopartaicles (ophthalmic TL-NPs formulations), and found them to show high uptake into ocular tissues