These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after Interaction Summary
You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications
Verapamil belongs to a class of drugs known as calcium verapamil simvastatin
Alcohol: Verapamil may increase blood alcohol concentrations and prolong its effects
Other medications can affect the removal of verapamil from your body Many drugs can interact with verapamil
Important warnings
Your doctor may need to change the doses of your medications or monitor you carefully for side effects
DRUG INTERACTIONS
Alternatives
lomitapide
For example, taking a cough medicine ( antitussive) and a drug to help
Professional
Consumer
, diltiazem, nicardipine, nifedipine, verapamil) may be of less benefit in these patients due to a fixed impedance to flow across the aortic valve and
Applies to: verapamil and Cialis (tadalafil) Verapamil may increase the blood levels and effects of tadalafil
You may be more likely to experience serious side effects such as irregular heart rhythm, fluid retention, swelling, heart failure, and excessively low blood pressure
Applies to: verapamil and Eliquis (apixaban) Verapamil may increase the blood levels of apixaban, which may result in a higher risk of bleeding complications
Talk to your doctor if you have any questions or concerns
Applies to: verapamil and Ubrelvy (ubrogepant) Verapamil can increase the blood levels of ubrogepant
Avoid driving or operating hazardous machinery until you know how the medication affects you, and use caution when getting up Applies to: verapamil and oxycodone
This can lead to serious and potentially fatal complications such as irregular heart rhythm and cardiac arrest, especially if you use more than the recommended doses of loperamide
This can increase the risk of side effects such as liver damage and a rare but serious condition called rhabdomyolysis that involves the breakdown of skeletal muscle tissue
Verapamil and cannabis (Schedule I substance) may have additive effects in lowering your blood pressure
Atrial Tachycardia (off-label) Bipolar Disorder (off-label) Cluster Headaches (off-label) Headache
This can increase the risk of side effects such as liver damage and a rare but serious condition called rhabdomyolysis that involves the breakdown of skeletal muscle tissue
Calcium Rich Products: Calcium-rich food products may lower the effectiveness of the drug
Limited drug-drug interaction studies have shown amiodarone use was associated with elevated levels of dabigatran and rivaroxaban, especially in patients with reduced renal function
This can cause fatigue, headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest pain, increased or decreased heartbeat, or irregular heartbeat