e
Many of these fungal infections are rare; however, they can be detrimental to the immunocompromised
Adults—200 milligrams (mg) 2 times a day for 1 week, followed by a no
Based on an oral
Methods: This systematic review and network meta-analysis compared the efficacy (as
Onychomycosis of the toenail, with or without fingernail involvement, due to dermatophytes (tinea unguium), and Itraconazole
If the nail of the big toe was completely involved, a fourth treatment cycle was administered
Itraconazole oral solution is only used to treat oropharyngeal or esophageal candidiasis (thrush, oral thrush)
Itraconazole is given at a dose of 200 mg daily for 6 weeks for fingernail onychomycosis and 12 weeks for toenail onychomycosis or, as a pulsed regimen, intermittently as 400 mg daily for one week per month for 3–4 consecutive months for toenail infections, and 2 months for fingernail infections
The dosage of itraconazole was Eight to 12 weeks for weekly dosing
Itraconazole has a high affinity for keratin, and In those with renal impairment, no adjustments in single-dose therapy are required; for multiple-dose therapy, either the dosage interval should be increased or the daily dosage should be reduced
Current indications include blastomycosis, histoplasmosis, aspergillosis and onychomycosis
Onychomycosis of the toenails with or without fingernail involvement Initial dose: 200mg twice daily for seven days
FDA-labeled itraconazole therapy for onychomycosis consists of 200 mg by mouth daily for twelve consecutive weeks, with
Introduction
23% Onychomycosis / drug therapy*
Treatment options for children are similar to those for adults and include both oral and topical therapies
25 years after initiation of therapy