; Target: Calcium Channel; Amlodipine is a dihydropyridine calcium antagonist (calcium ion antagonist or slow-channel blocker) that inhibits the movement of calcium ions into vascular smooth muscle cells and cardiac muscle cells
Substance Hierarchy
Amlodipine Chemical formula: C₂₀H₂₅ClN₂O₅ Molecular mass: 408
amlodipine: [ am-lo´dĭ-pēn ] a calcium channel blocking agent administered orally in the form of the besylate salt in treatment of hypertension and chronic stable and vasospastic angina
Keywords: amlodipine, blood pressure variability, calcium channel blockers, hypertension
Amlodipine inhibits the influx of extracellular calcium ions into myocardial and peripheral vascular smooth muscle cells, thereby preventing vascular and myocardial contraction
Figure 1: 13Amlodipine structure Use of the information, documents and data from the ECHA website is subject to the terms and conditions of this Legal Notice, and subject to other binding limitations provided for under applicable law, the information, documents and data made available on the ECHA website may be reproduced, distributed and/or used, totally or in part, for non-commercial purposes provided that ECHA is Visit ChemicalBook To find more (S)-Amlodipine(103129-82-4) information like chemical properties,Structure,melting point,boiling point,density,molecular formula,molecular weight, physical properties,toxicity information,customs codes
Record Protection Status Public definition
These agents are often classified into two major categories, either non-dihydropyridines or dihydropyridines
Amlodipine besylate monohydrate is a white crystalline powder with a molecular weight of 585
Acting as a vasodilator, amlodipine reduces blood pressure by relaxing the smooth muscle in the arterial wall, decreasing total peripheral resistance
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Both drugs have primarily arteriolar dilating properties with little effect on cardiac conduction and mechanical properties in the doses used clinically
USP REFERENCE STANDARDS FOR PURCHASE USP Amlodipine Besylate RS Name Amlodipine besylate Drug Entry Amlodipine
leg or ankle swelling
1 It is used alone or in combination with other medications to lower hypertension
It inhibits calcium-induced contractions in depolarized rat aorta with an IC 50 value of 1
CCBs are particularly effective against large vessel stiffness, one of the Amlodipine besylate is a white crystalline powder with a molecular weight of 567
The 2D chemical structure image of amlodipine is also called skeletal formula, which is the standard notation for organic molecules
General information
Vasodilators are medicines that open, also called dilate, blood vessels
Amlodipine besylate is a L-type calcium channel blocker which may be used for the treatment of angina pectoris and hypertension
Swelling in your legs or ankles
Amlodipine inhibits the influx of extracellular calcium ions into myocardial and peripheral vascular smooth muscle cells, thereby preventing vascular and myocardial contraction
5 mg, 5 DEFINITION
It has vasodilator effects without significant negative inotropic properties and has been used safely in patients with congestive heart failure
NIST/EPA/NIH 2020 is a trusted source of mass spectral data and software tools
InChI (IUPAC International Chemical Identifier) information of amlodipine Chemical Entities of Biological Interest (ChEBI) is a freely available dictionary of molecular entities focused on 'small' chemical compounds
Solid inclusion complexes were obtained by three methods: kneading, coprecipitation, and lyophilization, at a molar ratio of 1:1
Serious side effects may include kidney problems, low blood pressure Amlodipine is a calcium channel blocker, not a blood thinner
Amlodipine, sold under the brand name Norvasc among others, is a calcium channel blocker medication used to treat high blood pressure, coronary artery disease (CAD) and variant angina (also called Prinzmetal angina or coronary artery vasospasm, among other names)
Amlodipine works by blocking the voltage
Brand name: Norvasc
Brand names Brand names of combination products Why is this medication prescribed? Amlodipine is used alone or in combination with other medications
Substance
How it works Amlodipine may be used to treat heart conditions such as angina and high blood pressure
Use of the information, documents and data from the ECHA website is subject to the terms and conditions of this Legal Notice, and subject to other binding limitations
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Side effects of amlodipine include edema, palpitations, dizziness, and flushing, which are more common with the higher dose of 10 mg
Amlodipine is similar to nifedipine
These salts are considered interchangeably and the strength of the dosage form is determined in terms of the parent molecule, that is, AD []
0% of amlodipine besylate (C 20 H 25 ClN 2 O 5 ·C 6 H 6 O 3 S), calculated on the anhydrous basis
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1 It is used alone or in combination with other medications to lower hypertension
1 Acting as a vasodilator, amlodipine reduces blood pressure by relaxing the smooth muscle in the arterial wall, decreasing total peripheral resistance
Calcium channel blockers are used as antihypertensive drugs, i
The carbon atoms in the chemical structure of amlodipine are implied to be located at the corner(s) and hydrogen atoms attached to carbon atoms are not indicated – each carbon atom is considered to
The molecular weight of the internal standard desipramine was 266 and that of the protonated molecular ion in the Amlodipine is the only calcium channel blocker used in veterinary practice that has potent vasodilatory properties
Heart attack—pain or tightness in the chest, shoulders, arms, or jaw, nausea, shortness of breath, cold or clammy skin, feeling faint or lightheaded
In studies, less than 2 out of 100 people stopped taking amlodipine due to side effects
Definition