Both oral and intravenous preparations are available
CYP2D6 is a critical enzyme for many of the most commonly used beta-blockers
The plasma concentrations of metoprolol were determined using Reverse Phase-High Performance Liquid Chromatography (RP-HPLC) on the 1st day in single-dose
2 The time to resolution of inhibition varies based on factors such as the patient’s age; therefore, resolution Diltiazem, a moderate CYP3A4/P‐gp inhibitor, Second, we selected metoprolol, another commonly used medication recommended for heart rate control for AF but does not interact with DOACs, 50, 51 as the negative control exposure for diltiazem
Two different salts are available, metoprolol tartrate and metoprolol succinate
Take metoprolol at the same time each day
Off-label uses include supraventricular tachycardia and thyroid storm
Ubrelvy has interactions CYP3A4 Inhibitors: Importantly, CYP enzymes may be responsible for the metabolism (at least partially) of approximately 75% of all drugs, with the CYP3A subfamily responsible for nearly half of this activity
2
Gleichzeitig hemmt Metoprolol dieses Enzym, wodurch Wechselwirkungen mit anderen Wirkstoffen, die über CYP2D6 abgebaut werden, möglich sind