Interaction between warfarin and amiodarone

In patients receiving amiodarone, limit dosages. Amiodarone strongly potentiates the anticoagulant effects of warfarin, resulting in prolongation of the international normalized ratio (INR) and increased risk of bleeding

2024-03-29
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  1. 1056/NEJM198103123041116
  2. Interaction between warfarin sodium and amiodarone N Engl J Med
  3. 94, p < 0
  4. Saint John's wort
  5. Amiodarone decreased the total body clearance of
  6. Severity: Severe
  7. 8,18