Mechanism of Action
Donepezil may increase the neuromuscular blocking activities of Moxisylyte
Donepezil is a drug that has been used to treat AD safely for many years; our findings suggest that it might be repurposed to treat CNS demyelinating diseases
Randomized controlled trials (RCTs) evaluating the effectiveness and side effect profile of different dosages of donepezil used in severe AD were identified
It inhibits voltage-activated sodium currents reversibly and
Donepezil has demonstrated a range of effects, including protecting against amyloid β, ischaemia and
Here, we developed combinatorial drugs targeting multifactorial mechanisms underlying key components in ALS disease progression
Every element of the public health bureaucracy is turned into a fanatical modern equivalent of Operation Rescue
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Maintenance dose: 10 mg orally once a day, after the patient has been on an initial dose of 5 mg once a day for 4 to 6 weeks
Donepezil is well tolerated; the most common adverse events are predictable from its cholinergic
Donepezil is an inexpensive drug used to treat mild to moderate dementia caused by Alzheimer's disease
The precise mechanism(s) of action of donepezil in patients with dementia of the Alzheimer's type (Alzheimer's disease) has not been fully elucidated
The most common side effects of donepezil are diarrhoea, headaches and feeling sick (nausea)
A fixed-combination preparation consisting of memantine and donepezil is commercially available for the treatment of moderate to severe dementia of the Alzheimer's type in patients receiving donepezil hydrochloride at a stable dosage of 10 increase in sexual desire or performance
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Patient and carer advice Patient and carer advice For donepezil hydrochloride
It's taken as a pill once a day or as an extended-release capsule twice a day
Donepezil will not cure Alzheimer's disease, and it will not stop the disease from getting worse
This medicine is available only with your
For example, during the pivotal trials of donepezil, patients randomized to donepezil 10 mg day −1 received donepezil 5 mg day −1 for the first 7 days and then 10 mg day −1 thereafter
If you're bothered by side effects, tell your doctor
Does donepezil interact with my other drugs? Enter other medications to view a detailed report
It is a once-weekly donepezil transdermal system
Donepezil is prescribed for people who have dementia which is associated with Alzheimer's disease
Common side effects
Side effects are less likely to happen if your doctor starts you on the lower 5mg dose for at least a month
Acetylcholinesterase inhibitors, such as donepezil, work by The exact mechanism that underlies donepezil’s effect in promoting OPC to OL differentiation remains unclear