Ingestion of >10 tablets of verapamil or diltiazem XR can cause life-threatening toxicity
Symptoms of a calcium-channel blocker overdose include: Agitation (hyperactivity) and delirium (confused thinking and possible hallucinations) Breathing
Also tell your health care professional if you
Management: Initiate lovastatin at a maximum adult dose of 10 mg/day, and do not
Signs and symptoms of toxicity: Signs of toxicity include vomiting, decreased heart rate, low blood pressure, altered mental status, diarrhea and weakness
Starting with 30 mg four times daily, before meals and at bedtime, dosage is increased gradually (given in divided doses three or four times daily) at 1- to 2-day
This may cause signs or symptoms that include: Lightheadedness; Dizziness; Fainting; Difficulty breathing; Fluid retention
Possible signs of toxicity include: Dizziness, agitation, or confusion
25 mg/kg; may repeat in 15 min with a dose of 0
Methamphetamine toxicity: treatment with a benzodiazepine versus a butyrophenone
Verapamil and diltiazem are the CCBs most commonly implicated in severe CVS toxicity following overdose
Critical care management of verapamil and diltiazem overdose with a focus on vasopressors: a 25
Clinical sequelae include all grades of heart block, hypotension and ultimately death
Hence, we present a case of complete atrioventricular AV block in a patient receiving sustained- release diltiazem on a chronic
Of cases with known outcome, most patients recovered and in cases with a fatal outcome, the majority involved multiple drug ingestion
1 Hypertension - Initiate dosing at 180 to 240 mg once daily 3 DOSAGE FORMS AND STRENGTHS
The patient will not have the usual signs and symptoms of hypoglycemia or hyperglycemia
general feeling of discomfort or illness
Of cases with known outcome, most patients recovered and in cases with a fatal outcome, the majority involved multiple drug ingestion
Events observed following diltiazem overdose included bradycardia, hypotension, heart block, and cardiac failure
Events observed following diltiazem overdose included bradycardia, hypotension, heart block, and cardiac failure
5 times normal
The 120 mg capsules are hard shell gelatin capsules with a dark pink opaque cap and a dark pink opaque body, imprinted with “Y” on the cap and “562” on the body with black ink, filled with white to off-white pellets
Reports of serious CCB toxicity have increased due to the widespread use of this class of medication