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It is used against HIV infections as a fixed-dose combination with another protease inhibitor, ritonavir ( lopinavir/ritonavir )
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In the United States, lopinavir-ritonavir 200 mg-50 mg tablets are only
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Lopinavir is an antiretroviral protease inhibitor used in combination with other antiretrovirals in the treatment of HIV-1 infection
A randomized, controlled, open-label trial of lopinavir–ritonavir in patients with severe COVID-19 shows no benefit for the primary endpoint beyond standard care but
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Tablet: Lopinavir 500 mg/ritonavir 125 mg twice daily
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Lopinavir Lopinavir (LPV) is an antiretroviral protease inhibitor used in combination with ritonavir (booster) in HIV infection therapy and prevention
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In patients admitted to hospital with COVID-19, lopinavir–ritonavir was not associated with reductions in 28-day mortality, duration of hospital stay, or risk of progressing to invasive mechanical ventilation or death
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In the trial of lopinavir–ritonavir involving patients with severe Covid-19, Cao et al