When given by infusion amiodarone may reduce drop size and, if appropriate, adjustments should be made to the rate of infusion
5 seconds
ing the dose or discontinuing amiodarone
5 mg/min IV for the following 18 hours
Symptomatic bradycardia (without pacemaker)
Prescribe 1200 mg of amiodarone to be administered as a continuous infusion (ideally via a CVC)
Premixed solutions are Maximum dose: Initial infusion rate: 30 mg/min Duration of therapy: Until ventricular arrhythmias stabilize (most patients require 48 to 96 hours); maintenance infusion of up to 0
5 seconds
Table 3: RECOMMENDATIONS FOR ORAL DOSAGE AFTER INTRAVENOUS INFUSION : Reference ID: 4853130
(per Manufacturer), South San Francisco, CA, 2015 Amiodarone 1
Product This loading dose worksheet is intended to guide medical, nursing and pharmacy staff in the safe and appropriate prescribing and administration of intravenous amiodarone loading doses in adults
v
4 times the MRHD when compared on a body surface area basis), maternal toxicity (as evidenced by reduced weight gain and food consumption) and embryotoxicity (as evidenced by increased When repeated or continuous infusion is anticipated, administration by a central venous catheter is recommended
The standard recommended dose is 5mg/kg bodyweight given by intravenous infusion over a period of 20 minutes to 2 hours
Following a loading dose of 300 mg/30 mins, two Who can administer
75 mg/kg
Amiodarone (Intravenous Route) Drug information provided by: Merative, Micromedex
Peak serum concentrations after 15-minute infusions in healthy volunteers range from 5 to 41 mg/L
This medicine is to be given only by or under the supervision of your doctor
5 mg/min on a body surface area basis) during gestation days 8 to 16 (organogenesis)
7, and 1
5 mg/ml with a total dose of 150 mg diluted in 100 ml of dextrose 5% in water (D5W) was given within 30 minutes
The primary outcome was the ability of amiodarone in rate control lower than 95 beats per minute (BPM) and maintaining it during 24-h study period
5 mg/min on a body surface area basis) during gestation days 8 to 16 (organogenesis)
Amiodarone was administered by continuous intravenous infusion to rats at dosages of 25, 50, or 100 mg/kg per day (about 0
Available is 25,000 units of heparin in 500 mL 0
Usual Pediatric Dose for Congestive Heart Failure
hepatic & renal dysfunction) Dose
infusions, compounded oral liquid medications, pediatric continuous IV infusions, doses for liquid medications, intravenous intermittent ADULT CONTINUOUS INFUSION STANDARDS 6 Drug Concentration Standards Genentech, Inc
6 mg/mL mg/min Yes 1
5 to 1 mg/min2 OR 800 mg PO daily x 1 week, then 600 mg PO daily x 1 week, then 400 mg PO daily x 4 to 6 weeks1,2 Maintenance: 200-400 mg PO daily Elderly: Initiate dosage at the lower end of the adult range Hepatic Impairment: No specific guidelines available
ozanimod increases toxicity of milrinone by sympathetic (adrenergic) effects, including increased blood pressure and heart rate
Slow titration to sub-maximal doses may have Amiodarone was commenced as an IV loading dose of 300mg following a continuous IV infusion of 600mg at a maximum rate of 72mg per hour
This dose may be repeated 1-2 times for refractory VFib or pulseless V-tach
Loading dose 0
maintenance dose: continuous IV infusion: 20 to 80 mcg/kg/minute; maximum dose: 2 g/day
6 mg/mL mcg/kg/ min* Yes - 1
Amiodarone Injection Dosage and Administration
Continuous IV infusion has also been used
Loading dose followed by a continuous infusion: Prescribe a single loading dose of 5 mg/kg (max
0
8
Injection solution contains benzyl alcohol
(10 breaths/min) with continuous chest compressions Drug Therapy • Epinephrine IV/IO dose: 1 mg every 3-5 minutes • Amiodarone IV/IO dose: First dose: 300 mg bolus
2 g per day
A nurse or other trained health professional will give you this medicine in a hospital
Oral dosing: The recommended daily oral dose for this approach is 400 mg of
Following bolus administration: 1 to 4 mg/min continuous IV infusion Comments: defibrillation, and vasopressor therapy as an alternative to amiodarone Usual Adult Dose for Cardiac Arrhythmia
5 mg/min on a body surface area basis) during gestation days 8 to 16 (organogenesis)
Amiodarone was administered by continuous intravenous infusion to rats at dosages of 25 mg/kg per day, 50 mg/kg per day, or 100 mg/kg per day (about 0
Amiodarone’s adverse effects can be divided into two categories: those which occur during the intravenous loading dose and those associated with chronic oral administration
The recommended total dose over 24 hours should not exceed 2
For the peripheral venous catheter infusion, an amiodarone loading concentration of 1
3, 0
Dosage Calculation 3