Diet and exercise constitute the first-line treatment for mild and moderate
Fibrates are the drugs of choice when treating isolated elevated triglycerides
Payam Mehranpour answered Internal Medicine - Cardiology 25 years experience Lipid lowering agent: Few of the alternatives
Payam Mehranpour answered Specializes in Internal Medicine - Cardiology Few of
Many other drug classes cannot
The combination of a statin with a fibrate carries an increased risk of muscle-related side-effects (including rhabdomyolysis) and should Gemfibrozil (Lopid) and fenofibrate (TriCor) appear equally safe and effective
30 major drug interactions (212 brand and generic names); 51 moderate drug interactions (145 brand and generic names); 4 minor drug interactions (8 brand and generic names); A total of 373 drugs are known to interact with
This may help prevent the development of pancreatitis (inflammation or swelling of the pancreas) caused by high levels of Fenofibrate has an average rating of 5
Canadian brand names are in brackets
56% of reviewers reported a positive effect, while 19% reported a negative effect
The biggest risk with this interaction is rhabdomyolysis, so assessment of CPK might be an appropriate way to help monitor for the potential interaction between gemfibrozil and statins
Pediatric Use Applies to gemfibrozil: oral tablet
Pharmacokinetic studies of ezetimibe with gemfibrozil and fenofibrate resulted in a non-significant increase in the oral bioavailability of ezetimibe by a factor of 1
consider the use of alternative therapy against risks and benefits of a lower dose of metformin; Pregnancy and Lactation
- 113 alternative drugs to Gemfibrozil - 4,441 Gemfibrozil side effects and drug interactions Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world
Condition
Abrocitinib is a CYP2C9 and CYP2C19 substrate
All patients had hypertension and were overweight, male, and at high cardiovascular risk
It is important to make sure your doctor is a part Gemfibrozil is available in multiple generic forms and under the brand name of Lopid as tablets of 600 mg
There was no difference in mortality between the gemfibrozil and placebo groups